中文名稱    CD72蛋白抗體    
英文名稱    CD72  
別    名    B-cell differentiation antigen CD72; CD72b; LYB2; B cell differentiation antigen CD72; CD72 antigen; CD72 molecule; CD72c; Ly-19; Ly-32; Ly-m19; Lyb-2; Lyb2; LYB2, mouse, homolog of; Lymphocyte antigen 32; MGC108873; CD72_HUMAN.      
研究領(lǐng)域    腫瘤  免疫學(xué)  干細(xì)胞  細(xì)胞表面分子  糖蛋白  b-淋巴細(xì)胞      
抗體來源    Rabbit    
克隆類型    Polyclonal    
交叉反應(yīng)    Human, Mouse, Rat, Dog, Cow,     
產(chǎn)品應(yīng)用    ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg/Test IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    
分 子 量    40kDa    
細(xì)胞定位    細(xì)胞膜     
性    狀    Lyophilized or Liquid    
濃    度    1mg/ml    
免 疫 原    KLH conjugated synthetic peptide derived from human CD72:4-110/359     
亞    型    IgG    
純化方法    affinity purified by Protein A    
儲 存 液    0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.    
保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    
PubMed    PubMed    


產(chǎn)品介紹    CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface molecules such as the asialoglycoprotein receptors, CD23 and the Kupffer cell receptor. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.    
CD72是一個(gè)重要的B細(xì)胞特異性受體。屬于II型膜內(nèi)糖蛋白成員中的細(xì)胞表面分子非唾液酸糖蛋白受體，雖然其分子功能目前還不清楚，但目前發(fā)現(xiàn)CD72的多態(tài)性與多種腫瘤有關(guān)。